Article
Evidences for increased expression variation of duplicate genes in budding yeast: from cis- to trans-regulation effects.
Nucleic acids research - 1 Feb 2011
Dong Dong, Yuan Zineng, Zhang Zhaolei
Abstract excerpt
Duplicate genes tend to have a more variable expression program than singleton genes, which was thought to be an important way for the organism to respond and adapt to fluctuating environment. However, the underlying molecular mechanisms driving such expression variation remain largely unexplored. In this work, we first rigorously confirmed that duplicate genes indeed have higher gene expression variation than...
Topics
- Chromatin
- Epigenesis, Genetic
- Gene Expression
- Gene Expression Regulation, Fungal
- Genes, Duplicate
- Genetic Variation
- Histones
- Saccharomyces cerevisiae
- Transcription Factors