A yeast hybrid provides insight into the evolution of gene expression regulation.

doi:10.1126/science.1169766

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A yeast hybrid provides insight into the evolution of gene expression regulation.

Science (New York, N.Y.) - 1 May 2009

Tirosh Itay, Reikhav Sharon, Levy Avraham A, Barkai Naama

Abstract excerpt

During evolution, novel phenotypes emerge through changes in gene expression, but the genetic basis is poorly understood. We compared the allele-specific expression of two yeast species and their hybrid, which allowed us to distinguish changes in regulatory sequences of the gene itself (cis) from...

Topics

Culture Media
Evolution, Molecular
Gene Expression Profiling
Gene Expression Regulation, Fungal
Genes, Fungal
Genetic Variation
Genome, Fungal
Glycerol
Hot Temperature
Hybridization, Genetic
Mutation
Oligonucleotide Array Sequence Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Regulatory Sequences, Nucleic Acid

Saccharomyces

Saccharomyces cerevisiae

Species Specificity

TATA Box

Source

Open in PubMed

Identifiers

PMID: 19407207
DOI: 10.1126/science.1169766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19407207-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A yeast hybrid provides insight into the evolution of gene expression regulation.PMID 19407207Read ↗

Evolutionary changes in cis and trans gene regulation.Semantic proximity Read ↗

Cis-regulatory variants affect gene expression dynamics in yeast.Semantic proximity Read ↗

Cis-Regulatory Divergence in Gene Expression between Two Thermally Divergent Yeast Species.Semantic proximity Read ↗

Evolutionary Dynamics of Regulatory Changes Underlying Gene Expression Divergence among Saccharomyces Species.Semantic proximity Read ↗

Gene Regulation and Speciation.Semantic proximity Read ↗

Accumulation of cis- and trans-regulatory variations is associated with phenotypic divergence of a complex trait between yeast species.Semantic proximity Read ↗

The roles of cis- and trans-regulation in the evolution of regulatory incompatibilities and sexually dimorphic gene expression.Semantic proximity Read ↗

RNA-seq analysis of allele-specific expression, hybrid effects, and regulatory divergence in hybrids compared with their parents from natural populations.Semantic proximity Read ↗

Regulatory divergence between parental alleles determines gene expression patterns in hybrids.Semantic proximity Read ↗

Inferring regulatory mechanisms from patterns of evolutionary divergence.Semantic proximity Read ↗

Natural gene expression variation studies in yeast.Semantic proximity Read ↗

Gene expression divergence and the origin of hybrid dysfunctions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.