Article
Intra and Interspecific Variations of Gene Expression Levels in Yeast Are Largely Neutral: (Nei Lecture, SMBE 2016, Gold Coast).
Molecular biology and evolution - 1 Sept 2017
Yang Jian-Rong, Maclean Calum J, Park Chungoo, Zhao Huabin, Zhang Jianzhi
Abstract excerpt
It is commonly, although not universally, accepted that most intra and interspecific genome sequence variations are more or less neutral, whereas a large fraction of organism-level phenotypic variations are adaptive. Gene expression levels are molecular phenotypes that bridge the gap between genotypes and corresponding organism-level phenotypes. Yet, it is unknown whether natural variations in gene expression...
Topics
- Adaptation, Physiological
- Environment
- Evolution, Molecular
- Gene Expression
- Gene Expression Profiling
- Gene Expression Regulation, Fungal
- Genetic Variation
- Genome, Fungal
- Genotype
- Mutation