Interferon lambda 4 genotype and pathway in alcoholic hepatitis.

doi:10.1080/00365521.2021.1874046

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Article

Interferon lambda 4 genotype and pathway in alcoholic hepatitis.

Scandinavian journal of gastroenterology - 1 Mar 2021

Støy Sidsel, Terczynska-Dyla Ewa, Veidal Sanne Skovgård, Rigbolt Kristoffer, Vilstrup Hendrik, Grønbaek Henning, Hartmann Rune, Sandahl Thomas D

Abstract excerpt

OBJECTIVES: Single nucleotide polymorphisms within the interferon lambda 4 (IFNL4) gene influence liver inflammation and fibrosis in chronic liver disease. We investigated whether this is also the case during acute liver disease, alcoholic hepatitis. We, therefore, related variants within the IFNL4 gene to the clinical course of acute alcoholic hepatitis, and characterized the activation state of the IFN lambda...

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PMID: 33602032
DOI: 10.1080/00365521.2021.1874046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.