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Article

Impact of Interferon Lambda 4 Genotype on Interferon-Stimulated Gene Expression During Direct-Acting Antiviral Therapy for Hepatitis C.

Hepatology (Baltimore, Md.) - 1 Sept 2018

Ramamurthy Narayan, Marchi Emanuele, Ansari M Azim, Pedergnana Vincent, Mclean Angela, Hudson Emma, Bowden Rory, Spencer Chris C A, Barnes Eleanor, Klenerman Paul

Abstract excerpt

New directly acting antivirals (DAAs) provide very high cure rates in most patients infected by hepatitis C virus (HCV). However, some patient groups have been relatively harder to treat, including those with cirrhosis or infected with HCV genotype 3. In the recent BOSON trial, genotype 3, patients with cirrhosis receiving a 16-week course of sofosbuvir and ribavirin had a sustained virological response (SVR)...

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Source

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Identifiers

PMID: 29534310
DOI: 10.1002/hep.29877
PMCID: PMC6207923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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