Article
High-resolution mapping identifies HLA class II associations with multifocal motor neuropathy.
Neurobiology of aging - 1 May 2021
Bos Jeroen W, Otten Henny G, Herraets Ingrid J T, Goedee H Stephan, Cats E A, de Hoop Talitha, Verduijn Willem, van der Pol W Ludo, van den Berg Leonard H
Abstract excerpt
OBJECTIVE: To gain further insight in the immunopathology underlying multifocal motor neuropathy (MMN) by exploring the association between MMN and the human leukocyte antigen (HLA) class II DRB1, DQB1, and DQA loci in depth and by correlating associated haplotypes to detailed clinical and anti-ganglioside antibody data. METHODS: We performed high-resolution HLA-class II typing for the DRB1, DQB1, and DQA1 loci...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
