Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DQB105:02, 05:03, and *03:01 alleles as risk factors for myasthenia gravis in a Spanish cohort.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Aug 2022

Salvado Maria, Caro Jose Luis, Garcia Cecilia, Rudilla Francesc, Zalba-Jadraque Laura, Lopez Eva, Sanjuan Elia, Gamez Josep, Vidal-Taboada Jose Manuel

Abstract excerpt

BACKGROUND: Myasthenia gravis (MG) is a very heterogenic chronic autoimmune disease caused by the failure of neuromuscular transmission. The HLA gene complex has conventionally been recognized as its main genetic risk and phenotype modifying factor. Our aim was to investigate the prevalence of HLA class I and II alleles and to identify possible risk factors for sporadic MG in a Spanish cohort. METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to HLA-DQ beta-Chains

Share to HLA-DRB1 Chains

Share to Myasthenia Gravis

Share to Risk Factors

Source

Identifiers

PMID: 35524016
DOI: 10.1007/s10072-022-06102-y

Genes

C7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DQB1*05:02, *05:03, and *03:01 alleles as risk factors for myasthenia gravis in a Spanish cohort.PMID 35524016Read ↗

Late onset myasthenia gravis is associated with HLA DRB1*15:01 in the Norwegian population.Semantic proximity Read ↗

Genetic heterogeneity within the HLA region in three distinct clinical subgroups of myasthenia gravis.Semantic proximity Read ↗

Juvenile myasthenia gravis in Norway: HLA-DRB1*04:04 is positively associated with prepubertal onset.Semantic proximity Read ↗

Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations.Semantic proximity Read ↗

Correlation Between the Prevalence of Myasthenia Gravis and the Frequency of Class II Human Leucocyte Antigen Alleles in Various Geographical Locations Around the WorldSemantic proximity Read ↗

Association between Cytotoxic T-Lymphocyte-Associated Antigen 4 (CTLA-4) Locus and Early-Onset Anti-acetylcholine Receptor-Positive Myasthenia Gravis in Serbian Patients.Semantic proximity Read ↗

Recent advances in genetic predisposition of myasthenia gravis.Semantic proximity Read ↗

A Myasthenia Gravis genomewide association study of three cohorts identifies Agrin as a novel risk locusSemantic proximity Read ↗

The autoimmune spectrum of myasthenia gravis: a Swedish population-based study.Semantic proximity Read ↗

Myasthenia gravis genome-wide association study implicates AGRN as a risk locus.Semantic proximity Read ↗

The associations of HLA-DRB1 gene polymorphisms with late-onset myasthenia gravis: a meta-analysis.Semantic proximity Read ↗

HLA class I and class II polymorphisms in Saudi patients with myasthenia gravis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.