Article
Genetic association of HLA-DRB1 multiple polymorphisms with dermatomyositis in Chinese population.
HLA - 1 Dec 2017
Lin J M, Zhang Y B, Peng Q L, Yang H B, Shi J L, Gu M L, Zhao W M, Wang G C
Abstract excerpt
Genetic variation in HLA plays an important role in the pathogenesis of dermatomyositis (DM). The aim of this study was to investigate the association of HLA class II with DM in China. Two hundred and twenty-four DM patients and 300 healthy controls were randomly enrolled at China-Japan Friendship Hospital. High-resolution typing of HLA-DRB1 alleles was performed by sequencing based typing. The HLA-DQA1 and...
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