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Article

Highly conserved extended haplotypes of the major histocompatibility complex and their relationship to multiple sclerosis susceptibility.

PloS one - 1 Jan 2018

Goodin Douglas S, Khankhanian Pouya, Gourraud Pierre-Antoine, Vince Nicolas

Abstract excerpt

OBJECTIVE: To determine the relationship between highly-conserved extended-haplotypes (CEHs) in the major histocompatibility complex (MHC) and MS-susceptibility. BACKGROUND: Among the ~200 MS-susceptibility regions, which are known from genome-wide analyses of single nucleotide polymorphisms (SNPs), the MHC accounts for roughly a third of the currently explained variance and the strongest MS-associations are for...

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Source

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Identifiers

PMID: 29438392
DOI: 10.1371/journal.pone.0190043
PMCID: PMC5810982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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