Investigating the molecular basis of drug action and response: chemocentric genomics and proteomics.

Abstract excerpt

The genomics and proteomics sciences have fundamentally changed the ways in which drug targets are being identified, characterized and validated. Here we review how genomics and proteomics research is improving our understanding of genetic determinants of drug susceptibility and response and, conversely, how organic small molecules mediate their pharmacological effects by modulating genome and proteome...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drug Resistance
• Share to Gene Expression Profiling
• Share to Mutation