Identification of protein binding partners of small molecules using label-free methods.

Abstract excerpt

INTRODUCTION: Drug discovery efforts across the globe are chasing new drug targets and novel mechanisms of action. To support the identification of novel mechanisms of action, phenotype-based drug screening has significantly increased over the last decade. Along with the rise in phenotypic screening, methods and technologies that can help to identify drug targets of phenotypically screened 'hits' have also...

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