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Article

Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models.

Brain pathology (Zurich, Switzerland) - 1 Jan 2006

Herzig Martin C, Van Nostrand William E, Jucker Mathias

Abstract excerpt

Cerebral amyloid angiopathy of the beta-amyloid type (Abeta-CAA) is a risk factor for hemorrhagic stroke and independently is believed to contribute to dementia. Naturally occurring animal models of Abeta-CAA are scarce and not well suited for the laboratory. To this end, a variety of transgenic mouse models have been developed that, similar to cerebral Abeta-amyloidosis in humans, develop either Abeta-CAA only...

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Identifiers

PMID: 16612981
DOI: 10.1111/j.1750-3639.2006.tb00560.x
PMCID: PMC8095938

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Source receipt: pubmed, retrieved 7 Sept 2026.

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