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Article

Cerebrovascular microRNA Expression Profile During Early Development of Alzheimer’s Disease in a Mouse Model

12 Nov 2021

Abstract excerpt

BACKGROUND: Emerging evidence demonstrates association of Alzheimer's disease (AD) with impaired delivery of blood oxygen and nutrients to and throughout the brain. The cerebral circulation plays multiple roles underscoring optimal brain perfusion and cognition entailing moment-to-moment blood flow control, vascular permeability, and angiogenesis. With currently no effective treatment to prevent or delay the...

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PMID: 34776451
DOI: 10.3233/jad-215223

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