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β-Arrestins 1 and 2 are critical regulators of inflammation

12 Sept 2013

Abstract excerpt

β-Arrestins 1 and 2 couple to seven trans-membrane receptors and regulate G protein-dependent signaling, receptor endocytosis and ubiquitylation. Recent studies have uncovered several unanticipated functions of β-arrestins, suggesting that the role of β-arrestins in cell signaling is much broader than originally thought. It is now recognized that β-arrestins can transduce receptor signaling independent of G...

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PMID: 24029143
DOI: 10.1177/1753425913501098

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