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Article

Quick validation of genetic quality for conditional alleles in mice.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Apr 2021

Nakata Hatsumi, Hashimoto Tomomi, Yoshiki Atsushi

Abstract excerpt

Site-specific conditional inactivation technologies using Cre-loxP or Flp-FRT systems are becoming increasingly important for the elucidation of gene function and disease mechanism in vivo. A large number of gene knockout mouse models carrying complex conditional alleles have been generated by global community efforts and made available for biomedical researchers. The structures of conditional alleles in these...

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PMID: 33540482
DOI: 10.1111/gtc.12834
PMCID: PMC8247991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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