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Article

Long-term persistence of both functional and non-functional alleles at the leukocyte immunoglobulin-like receptor A3 (LILRA3) locus suggests balancing selection.

Human genetics - 1 May 2006

Hirayasu Kouyuki, Ohashi Jun, Kashiwase Koichi, Takanashi Minoko, Satake Masahiro, Tokunaga Katsushi, Yabe Toshio

Abstract excerpt

The leukocyte immunoglobulin-like receptor (LILR) family consists of 13 loci, and a number of variations have been identified in these genes. Some polymorphisms of the LILR genes are reported to be associated with susceptibility to diseases such as rheumatoid arthritis and multiple sclerosis. LILRA3, one of the LILR genes, exhibits a presence or absence variation due to a 6.7-kb deletion in various populations....

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Source

Identifiers

PMID: 16501917
DOI: 10.1007/s00439-006-0152-y

Genes

LILRA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Long-term persistence of both functional and non-functional alleles at the leukocyte immunoglobulin-like receptor A3 (LILRA3) locus suggests balancing selection.PMID 16501917Read ↗

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