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Article

Quantitative Proteomic Analysis of the Senescence-Associated Secretory Phenotype by Data-Independent Acquisition.

Current protocols - 1 Feb 2021

Neri Francesco, Basisty Nathan, Desprez Pierre-Yves, Campisi Judith, Schilling Birgit

Abstract excerpt

Cellular senescence is a complex stress response that induces an essentially permanent cell cycle arrest and a complex secretory phenotype termed the senescence-associated secretory phenotype (SASP), which drives numerous aging pathologies. Characterization of the SASP can provide insights into aging and disease mechanisms, aging biomarker candidates, and targets for counteracting the deleterious effects of...

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Identifiers

PMID: 33524224
DOI: 10.1002/cpz1.32
PMCID: PMC7898702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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