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A plasma proteomic signature links secretome of senescent monocytes to aging- and obesity-related clinical outcomes in humans

2024-08-20

Abstract excerpt

<title>Abstract</title> <p>Cellular senescence increases with age and contributes to age-related declines and pathologies. We identified circulating biomarkers of senescence associated with diverse clinical traits in humans to facilitate future non-invasive assessment of individual senescence burden and efficacy testing of novel senotherapeutics. Using a novel nanoparticle-based proteomic workflow, we profiled th...

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Literature Corpus work
d83ba332-dbd1-5c8f-bf4c-de12b4953e7a
DOI
10.21203/rs.3.rs-4844258/v1
Open publication

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A plasma proteomic signature links secretome of senescent monocytes to aging- and obesity-related clinical outcomes in humansDOI 10.21203/rs.3.rs-4844258/v1
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