Article

A deep-learning based biomarker of systemic cellular senescence burden to predict mortality and health outcomes

2026-03-24

Abstract excerpt

<h4>Introduction</h4> The accumulation of senescent cells is a recognized hallmark of biological aging and is associated with the onset of multiple chronic medical conditions. Senescent cells exhibit a distinct secretory profile, known as the senescence-associated secretory phenotype (SASP), which can propagate cellular senescence to neighboring and distant tissues. Measuring SASP factors in blood serves as a pra...

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Literature Corpus work: 0775b109-14e6-5960-b18d-c187b7bf8e3b
DOI: 10.64898/2026.03.20.26348913

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