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Article

Genetic susceptibility and HLA association in autoimmune hepatitis among Yemeni patients.

BMC immunology - 21 May 2026

Farie Waleed Qassem, Bahaj Saleh Salem, Al-Madhagi Anwar Kassem, Ali Sarosh Sher, Noman Aref, Alkassar Waleed Yahya

Abstract excerpt

BACKGROUND: Autoimmune hepatitis (AIH) is a chronic, immune-mediated liver disease characterized by the progressive destruction of hepatocytes, often leading to cirrhosis and liver failure. Genetic predisposition, particularly the involvement of human leukocyte antigen (HLA) alleles, is well-documented in the pathogenesis of AIH. However, the specific HLA associations in the Yemeni population remain unexplored,...

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Identifiers

PMID: 42163120
DOI: 10.1186/s12865-026-00838-4
PMCID: PMC13192006

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