Article
Novel insights into autoimmune liver diseases provided by genome-wide association studies.
Journal of autoimmunity - 1 Oct 2013
Mells George F, Kaser Arthur, Karlsen Tom H
Abstract excerpt
Autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are complex disorders, resulting from the interaction of genetic and environmental factors. For many years, investigators have attempted to delineate the genetic architecture of these conditions, aiming to elucidate disease pathogenesis and identify molecular targets for pharmacotherapy. Early genetic studies...
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