Article
Genetic Risk and the Development of Autoimmune Liver Disease.
Digestive diseases (Basel, Switzerland) - 1 Jan 2015
Karlsen Tom H, Chung Brian K
Abstract excerpt
Primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) have collectively been recognized as autoimmune liver diseases. They have all been subjected to genome-wide association studies (GWAS) and several dozens susceptibility loci have been determined. The predominant feature of the genetic findings is that of a strong association with the human leukocyte antigen (HLA)...
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