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Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification

25 Jan 2021

Abstract excerpt

BACKGROUND: Genome-wide DNA methylation profiling has recently been developed into a tool that allows tumor classification in central nervous system tumors. Extracellular vesicles (EVs) are released by tumor cells and contain high molecular weight DNA, rendering EVs a potential biomarker source to identify tumor subgroups, stratify patients and monitor therapy by liquid biopsy. We investigated whether the DNA in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33508126
DOI: 10.1093/neuonc/noab012

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