Article

Genome-wide methylation profiling reveals extracellular vesicle DNA as an ex vivo surrogate of cancer cell-derived DNA

2023-12-21

Abstract excerpt

<title>Abstract</title> <p>Extracellular vesicle-derived DNA (evDNA) encapsulates the complete genome and mutational status of cells; however, whether cancer cell-derived evDNA mirrors the epigenetic features of parental genomic DNA remains uncertain. This study aimed to assess and compare the DNA methylation patterns of evDNA from cancer cell lines and primary cancer tissues with those of the nuclear genomic DNA...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e54cea10-78b2-51bb-9ef1-ad7cfa787121
DOI: 10.21203/rs.3.rs-3738922/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide methylation profiling reveals extracellular vesicle DNA as an ex vivo surrogate of cancer cell-derived DNADOI 10.21203/rs.3.rs-3738922/v1Read

Characteristics and Clinical Application of Extracellular Vesicle-Derived DNASemantic proximity Read

Unravelling the Significance of Extracellular Vesicle‐Associated DNA in Cancer Biology and Its Potential Clinical ApplicationsSemantic proximity Read

Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classificationSemantic proximity Read

Extracellular vesicle-associated DNA: ten years since its discovery in human bloodSemantic proximity Read

Extracellular Vesicle Gene Expression Enables Sensitive Detection of Colorectal NeoplasiaSemantic proximity Read

Plasma cell-free DNA methylome profiling in pre- and post-surgery oral cavity squamous cell carcinomaSemantic proximity Read

Genome-wide DNA Methylation Profiling of Cell-Free Serum DNA in Esophageal Adenocarcinoma and Barrett EsophagusSemantic proximity Read

Unraveling extracellular vesicle DNA: Biogenesis, functions, and clinical implicationsSemantic proximity Read

Discovery of Double-Stranded Genomic DNA in Circulating Exosomes.Semantic proximity Read

Unveiling targeted cell-free DNA methylation regions through paired methylome analysis of tumor and normal tissuesSemantic proximity Read

Circulating tumor cells: from new biological insights to clinical practiceSemantic proximity Read

Characteristics and Changes of DNA in Extracellular Vesicles.Semantic proximity Read