Article
Roles of the C-Terminal Amino Acids of Non-Hexameric Helicases: Insights from Escherichia coli UvrD.
International journal of molecular sciences - 20 Jan 2021
Yokota Hiroaki
Abstract excerpt
Helicases are nucleic acid-unwinding enzymes that are involved in the maintenance of genome integrity. Several parts of the amino acid sequences of helicases are very similar, and these quite well-conserved amino acid sequences are termed "helicase motifs". Previous studies by X-ray crystallography and single-molecule measurements have suggested a common underlying mechanism for their function. These studies...
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