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Spontaneous Lung Fibrosis Resolution Reveals Novel Antifibrotic Regulators

25 Jan 2021

Abstract excerpt

Fibroblast activation is transient in successful wound repair but persistent in fibrotic pathologies. Understanding fibroblast deactivation during successful wound healing may provide new approaches to therapeutically reverse fibroblast activation. To characterize the gene programs that accompany fibroblast activation and reversal during lung fibrosis resolution, we used RNA sequencing analysis of flow sorted...

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Identifiers

PMID: 33493091
DOI: 10.1165/rcmb.2020-0396oc

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