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Article

Complex formation and reciprocal regulation between GSK3β and C3G.

Biochimica et biophysica acta. Molecular cell research - 1 Apr 2021

Sriram Divya, Dayma Kunal, Devi Ambure Sharada, Raghawan Akhouri Kishore, Rawat Shivali, Radha Vegesna

Abstract excerpt

GSK3β, a ubiquitously expressed Ser/Thr kinase, regulates cell metabolism, proliferation and differentiation. Its activity is spatially and temporally regulated dependent on external stimuli and interacting partners, and its deregulation is associated with various human disorders. In this study, we identify C3G (RapGEF1), a protein essential for mammalian embryonic development as an interacting partner and...

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PMID: 33450305
DOI: 10.1016/j.bbamcr.2021.118964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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