Article
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype.
Journal of gastroenterology - 1 Jul 2010
Jürgens Matthias, Brand Stephan, Laubender Rüdiger P, Seiderer Julia, Glas Jürgen, Wetzke Martin, Wagner Johanna, Pfennig Simone, Tillack Cornelia, Beigel Florian, Weidinger Maria, Schnitzler Fabian, Kreis Martin E, Göke Burkhard, Lohse Peter, Herrmann Karin, Ochsenkühn Thomas
Abstract excerpt
BACKGROUND AND AIMS: We analyzed the prevalence of concomitant intestinal stenosis in patients with fistulizing Crohn's disease (CD), including the NOD2/CARD15 and IL23R genotype status. METHODS: Medical records of n = 1,110 patients with inflammatory bowel diseases were screened for patients wit...
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