Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Mutations and Small Bowel Ulcerating Disease: Role in Diagnosis?

Current gastroenterology reports - 21 May 2025

Modi Rangesh, Storozuk Tanner, Setia Namrata

Abstract excerpt

PURPOSE OF REVIEW: This review examines the role of genetic variations in the pathogenesis of small bowel (SB) ulcers associated with Crohn's disease (CD), NSAID enteropathy, and Cryptogenic Multifocal Ulcerous Stenosing Enteritis (CMUSE)/Chronic Non-Specific Ulcers of the Small Intestine (CNSU), aiming to address current diagnostic challenges. RECENT FINDINGS: Advances in molecular genetics have revealed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Crohn Disease
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Intestinal Diseases

Share to Intestine, Small

Share to Nod2 Signaling Adaptor Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 40399663
DOI: 10.1007/s11894-025-00978-4
PMCID: PMC12095398

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Mutations and Small Bowel Ulcerating Disease: Role in Diagnosis?PMID 40399663Read ↗

Crohn's disease-related single nucleotide polymorphisms are associated with ileal pouch afferent limb stenosis.Semantic proximity Read ↗

Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project.Semantic proximity Read ↗

Association and Pathogenic Mechanisms of Solute Carrier-related Genes in Crohn's DiseaseSemantic proximity Read ↗

Translating IBD Genomics into Clinical Practice.Semantic proximity Read ↗

Review article: genetic susceptibility and application of genetic testing in clinical management of inflammatory bowel disease.Semantic proximity Read ↗

150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibilitySemantic proximity Read ↗

Crohn-like Disease Affecting Small Bowel Due to Monogenic SLCO2A1 Mutations: First Cases of Chronic Enteropathy Associated with SLCO2A1 Gene [CEAS] in France.Semantic proximity Read ↗

Diagnostic Yield of Next-generation Sequencing in Very Early-onset Inflammatory Bowel Diseases: A Multicentre StudySemantic proximity Read ↗

Novel Associations Between Genome-Wide Single Nucleotide Polymorphisms and MR Enterography Features in Crohn's Disease Patients.Semantic proximity Read ↗

A Novel Rare Missense Variation of the <em>NOD2</em> Gene: Evidences of Implication in Crohn’s DiseaseSemantic proximity Read ↗

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.Semantic proximity Read ↗

The genetics of inflammatory bowel disease: diagnostic and therapeutic implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.