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Article

Increased infiltration of regulatory T cells in hepatocellular carcinoma of patients with hepatitis B virus pre-S2 mutant.

Scientific reports - 13 Jan 2021

Teng Chiao-Fang, Li Tsai-Chung, Wang Ting, Liao Da-Ching, Wen Yi-Hsuan, Wu Tzu-Hua, Wang John, Wu Han-Chieh, Shyu Woei-Cherng, Su Ih-Jen, Jeng Long-Bin

Abstract excerpt

Hepatocellular carcinoma (HCC) is a frequent and deadly human cancer worldwide that is intimately associated with chronic hepatitis B virus (HBV) infection. Pre-S2 mutant is a HBV oncoprotein that plays important roles in HCC development and is linked to poor prognosis in HCC patients. However, the profiles of tumor-infiltrating lymphocytes in HCC tissues of pre-S2 mutant-positive patients remain unknown. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33441885
DOI: 10.1038/s41598-020-80935-5
PMCID: PMC7807072

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