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Article

Detection of hepatitis B virus pre-S mutants in plasma by a next-generation sequencing-based platform determines their patterns in liver tissues.

PloS one - 1 Jan 2020

Teng Chiao-Fang, Tsai Hung-Wen, Li Tsai-Chung, Wang Ting, Wang John, Shyu Woei-Cherng, Wu Han-Chieh, Su Ih-Jen, Jeng Long-Bin

Abstract excerpt

Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related death worldwide. Patients with hepatitis B virus (HBV) pre-S mutants in liver tissues or blood have been regarded as a high-risk population for HCC development and recurrence. Detection of pre-S mutants in clinical specimens is thus important for early diagnosis and prognosis of HCC to improve patient survival. Recently, we have...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B Surface Antigens

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Share to Liver Neoplasms

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Source

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Identifiers

PMID: 32559248
DOI: 10.1371/journal.pone.0234773
PMCID: PMC7304603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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