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Article

Hepatitis B Virus Pre-S Mutants as Biomarkers and Targets for the Development and Recurrence of Hepatocellular Carcinoma.

Viruses - 26 Aug 2020

Teng Chiao-Fang, Wu Han-Chieh, Su Ih-Jen, Jeng Long-Bin

Abstract excerpt

Chronic hepatitis B virus (HBV) infection is a major risk factor for the development of hepatocellular carcinoma (HCC), the leading cause of cancer-related death worldwide. Despite progress in the prevention and therapy of HCC, high incidence and recurrence rates of HCC remain big threats, resulting in poor patient survival. Effective biomarkers and targets of HCC are therefore urgently needed for better...

Topics

Antiviral Agents
Biomarkers
Carcinoma, Hepatocellular
Hepatitis B Surface Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver Cirrhosis
Liver Neoplasms
Mutant Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Recurrence, Local

Protein Precursors

Risk Factors

Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 32859114
DOI: 10.3390/v12090945
PMCID: PMC7552003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32859114-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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