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Next-Generation Sequencing-Based Quantitative Detection of Hepatitis B Virus Pre-S Mutants in Plasma Predicts Hepatocellular Carcinoma Recurrence.

Viruses - 24 Jul 2020

Teng Chiao-Fang, Li Tsai-Chung, Huang Hsi-Yuan, Lin Jia-Hui, Chen Wen-Shu, Shyu Woei-Cherng, Wu Han-Chieh, Peng Cheng-Yuan, Su Ih-Jen, Jeng Long-Bin

Abstract excerpt

Hepatocellular carcinoma (HCC) is among the most common and lethal human cancers worldwide. Despite curative resection, high recurrence of HCC remains a big threat, leading to poor patient outcomes. Hepatitis B virus (HBV) pre-S mutants, which harbor deletions over pre-S1 and pre-S2 gene segments of large surface proteins, have been implicated in HCC recurrence. Therefore, a reliable approach for detection of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32722114
DOI: 10.3390/v12080796
PMCID: PMC7472021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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