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Article

P2RX7 at the Host-Pathogen Interface of Infectious Diseases

12 Jan 2021

Abstract excerpt

evidence for the critical role these receptors play in mediating and modulating immune responses. Our observations indicate a role for P2X7 signaling in sensing damage-associated molecular patterns released by nearby infected cells to facilitate immunopathology or protection. In this review, we describe how P2RX7 signaling can play critical roles in numerous cells types in response to a diverse array of pathogens...

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PMID: 33441488
DOI: 10.1128/mmbr.00055-20

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