Article
The in vitro replication phenotype of hepatitis B virus (HBV) splice variant Sp1.
Virology - 1 Sept 2022
Sozzi V, McCoullough L, Mason H, Littlejohn M, Revill P A
Abstract excerpt
Although not critical for hepatitis B virus (HBV) replication, splicing of HBV pre-genomic RNA generates multiple HBV splice variants, some of which have been shown to impact replication of the genome-length HBV on which they rely for their replication. To date, all replication studies of splice variants have utilised truncated RNA or over-expression constructs, and studies utilising constructs that produce...
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