Article
Genomic Sequencing of Cancer-related Genes in Sinonasal Squamous Cell Carcinoma and Coexisting Inverted Papilloma.
Anticancer research - 1 Jan 2021
Uchi Ryutaro, Jiromaru Rina, Yasumatsu Ryuji, Yamamoto Hidetaka, Hongo Takahiro, Manako Tomomi, Sato Kuniaki, Hashimoto Kazuki, Wakasaki Takahiro, Matsuo Mioko, Nakagawa Takashi
Abstract excerpt
BACKGROUND: The genetic basis of sinonasal inverted papilloma (SNIP)-derived squamous cell carcinoma (SCC) has not yet been well characterized. AIM: To characterize the genetic abnormalities of SNIP and SNIP-derived SCC and to uncover their differences. MATERIALS AND METHODS: Mutations of 409 genes were analyzed using amplicon targeted sequencing in a total of six papilloma/carcinoma samples from four patients...
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