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Article

Assessment of TP53 and CDKN2A status as predictive markers of malignant transformation of sinonasal inverted papilloma.

Scientific reports - 21 Jun 2024

Kwon Soohyeon, Kim Jeong-Whun, Kim Eun Sun, Paik Jin Ho, Chung Jin-Haeng, Cho Sung-Woo, Won Tae-Bin, Rhee Chae-Seo, Wee Jee Hye, Kim Hyojin

Abstract excerpt

The mechanism and predictive biomarkers of sinonasal inverted papilloma (IP) transformation into squamous cell carcinoma (SCC) are still unclear. We investigated the genetic mutations involved and the predictive biomarkers. Fourteen patients with SCC arising from IP and six patients with IPs without malignant transformation (sIP) were included. DNA was extracted separately from areas of normal tissue, IP,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cyclin-Dependent Kinase Inhibitor p16

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Source

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Identifiers

PMID: 38902320
DOI: 10.1038/s41598-024-64901-z
PMCID: PMC11190283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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