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Article

Time Course of the Phenotype of Blood and Bone Marrow Monocytes and Macrophages in the Lung after Cigarette Smoke Exposure In Vivo.

International journal of molecular sciences - 9 Sept 2017

Oliveira da Silva Camila, Monte-Alto-Costa Andréa, Renovato-Martins Mariana, Viana Nascimento Filipe Jorge, Dos Santos Valença Samuel, Lagente Vincent, Pôrto Luís Cristóvão, Victoni Tatiana

Abstract excerpt

Alveolar macrophages play a central role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Monocytes are recruited from blood during inflammation and then mature into alveolar macrophages. The aim of this study was to investigate the effect of cigarette smoke (CS) at different times in lung macrophages and monocytes from blood and bone marrow in mice. Male mice (C57BL/6, n = 45) were divided...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28891938
DOI: 10.3390/ijms18091940
PMCID: PMC5618589

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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