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Article

IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2002

Zhu Zhou, Ma Bing, Zheng Tao, Homer Robert J, Lee Chun Geun, Charo Israel F, Noble Paul, Elias Jack A

Abstract excerpt

IL-13 stimulates inflammatory and remodeling responses and contributes to the pathogenesis of human airways disorders. To further understand the cellular and molecular events that mediate these responses, we characterized the effects of IL-13 on monocyte chemotactic proteins (MCPs) and compared the tissue effects of transgenic IL-13 in mice with wild-type (+/+) and null (-/-) CCR2 loci. Transgenic IL-13 was a...

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Source

Identifiers

PMID: 11884467
DOI: 10.4049/jimmunol.168.6.2953

Genes

CCR2
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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