Article
Two tSNPs in BRIP1 are associated with breast cancer during TDT analysis.
Molecular genetics & genomic medicine - 1 Feb 2021
Li Xuefei, Li Zhuo, Yang Miao, Luo Yan, Hu Li, Xiao Zhi, Huang Aji, Huang Juan
Abstract excerpt
OBJECTIVES: This study aimed to investigate and confirm the association between 15 single nucleotide polymorphisms of four susceptibility genes (NBS1, TP53, PTEN, and BRIP1) and the susceptibility of breast cancer. METHODS: The genome DNA was extracted from peripheral blood and tumor tissues from one hundred and seventeen core families. 15 SNPs were detected by PCR. The transmission disequilibrium test (TDT) and...
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