p.R72P, PIN3 Ins16bp polymorphisms of TP53 and CCR5?32 in north Indian breast cancer patients.

doi:10.7314/apjcp.2012.13.7.3305

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Article

p.R72P, PIN3 Ins16bp polymorphisms of TP53 and CCR5?32 in north Indian breast cancer patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Guleria Kamlesh, Sharma Sarika, Manjari Mridu, Uppal Manjit Singh, Singh Neeti Rajan, Sambyal Vasudha

Abstract excerpt

BACKGROUND: The present study aimed to find the prognostic implications of two polymorphisms in TP53 (p.R72P, PIN3 Ins16bp) and one in CCR5 (CCR5/32) in sporadic breast cancer patients. METHODS: DNA samples of 80 breast cancer patients and 80 age and gender matched unrelated healthy control individuals from Punjab, North West India were analyzed. RESULTS: For p.R72P, the genotype frequency was 13.8% (RR), 58.8%...

Topics

Adult
Aged
Alleles
Asian People
Breast Neoplasms
Case-Control Studies
Female
Genetic Predisposition to Disease
Genotype
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

India

Male

Middle Aged

Polymorphism, Genetic

Prognosis

Receptors, CCR5

Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 22994752
DOI: 10.7314/apjcp.2012.13.7.3305

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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