Article
Polymorphisms in telomere-associated genes, breast cancer susceptibility and prognosis.
European journal of cancer (Oxford, England : 1990) - 1 Nov 2009
Varadi Verena, Brendle Annika, Brandt Andreas, Johansson Robert, Enquist Kerstin, Henriksson Roger, Svenson Ulrika, Tavelin Björn, Roos Göran, Hemminki Kari, Lenner Per, Försti Asta
Abstract excerpt
Telomeres are essential structures for maintaining chromosomal stability and their length has been reported to correlate with cancer risk and clinical outcome. Single nucleotide polymorphisms (SNPs) in genes encoding telomere-associated proteins could affect telomere length and chromosomal stability by influencing gene expression or protein configuration in the telomeres. Here, we report the results of the first...
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