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Article

A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids

7 Dec 2017

Abstract excerpt

Gut epithelial organoids are routinely used to investigate intestinal biology; however, current culture methods are not amenable to genetic manipulation, and it is difficult to generate sufficient numbers for high-throughput studies. Here, we present an improved culture system of human induced pluripotent stem cell (iPSC)-derived intestinal organoids involving four methodological advances. (1) We adopted a...

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Cancer Cells and Metastasis
Pluripotent Stem Cells Research
Renal and related cancers

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29233552
DOI: 10.1016/j.stemcr.2017.11.004

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