Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses.

Frontiers in immunology - 1 Jan 2020

Ruschil Christoph, Gabernet Gisela, Lepennetier Gildas, Heumos Simon, Kaminski Miriam, Hracsko Zsuzsanna, Irmler Martin, Beckers Johannes, Ziemann Ulf, Nahnsen Sven, Owens Gregory P, Bennett Jeffrey L, Hemmer Bernhard, Kowarik Markus C

Abstract excerpt

Double negative (DN) (CD19+CD20lowCD27-IgD-) B cells are expanded in patients with autoimmune and infectious diseases; however their role in the humoral immune response remains unclear. Using systematic flow cytometric analyses of peripheral blood B cell subsets, we observed an inflated DN B cell population in patients with variety of active inflammatory conditions: myasthenia gravis, Guillain-Barré syndrome,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD19
Share to Antigens, CD20

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Communicable Diseases

Share to Encephalitis Viruses, Tick-Borne

Share to Immunity, Humoral

Share to Immunogenicity, Vaccine

Share to Influenza Vaccines

Share to Tumor Necrosis Factor Receptor Superfamily, Member 7

Source

Open in PubMed Open full text

Identifiers

PMID: 33391273
DOI: 10.3389/fimmu.2020.606338
PMCID: PMC7775384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses.PMID 33391273Read ↗

Specific induction of double negative B cells during protective and pathogenic immune responsesSemantic proximity Read ↗

Plasmablast-like Phenotype Among Antigen-Experienced CXCR5-CD19low B Cells in Systemic Lupus Erythematosus.Semantic proximity Read ↗

Two distinct durable human class-switched memory B cell populations are induced by vaccination and infectionSemantic proximity Read ↗

Costimulatory blockade depletes T peripheral helper, late-activated naïve, and DN2 B cells in rheumatoid arthritisSemantic proximity Read ↗

Multimodal repertoire analysis unveils B cell biology in immune-mediated diseasesSemantic proximity Read ↗

Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19Semantic proximity Read ↗

Maturation Trajectories and Transcriptional Landscape of Plasmablasts and Autoreactive B Cells in COVID-19Semantic proximity Read ↗

Double‐negative T cells: Setting the stage for disease control or progressionSemantic proximity Read ↗

Peripheral CD19hi B cells exhibit activated phenotype and functionality in promoting IgG and IgM production in human autoimmune diseases.Semantic proximity Read ↗

Novel B-cell subsets as potential biomarkers in idiopathic inflammatory myopathies: insights into disease pathogenesis and disease activitySemantic proximity Read ↗

IL-21 and IFN-alpha have both opposite and redundant role on human innate precursors and memory B-cell differentiationSemantic proximity Read ↗

Uncovering Immune Surveillance Deficiency in B Cell-Driven Autoimmune DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.