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Article

Implications of viral transmitted/founder (T/F) dynamics on vaccine development.

Human vaccines & immunotherapeutics - 3 Jul 2021

Mosa Alexander I

Abstract excerpt

Viral infection typically originates from a limited number of virions known as transmitted/founder (T/F) viruses. Studies of cross-species transmission, and intra-species transmission of antigenically variable viruses, indicates T/F variants may express distinct, transmissibility enhancing phenotypes. However, with evidence that transmissibility is associated with not only intrinsic virological features, such as...

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Identifiers

PMID: 33377822
DOI: 10.1080/21645515.2020.1861878
PMCID: PMC8189126

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