Article

A Remarkable Genetic Shift in a Transmitted/Founder Virus Broadens Antibody Responses Against HIV-1

2021-06-16

Abstract excerpt

A productive HIV-1 infection in humans is often established by transmission and propagation of a single transmitted/founder (T/F) virus, which then evolves into a complex mixture of variants during the lifetime of infection. An effective HIV-1 vaccine should elicit broad immune responses in order to block the entry of diverse T/F viruses. Currently, no such vaccine exists. An in-depth study of escape variants emer...

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Literature Corpus work: c343ef4b-7aa4-5ada-86d4-16f8929663e7
DOI: 10.1101/2021.06.16.448593

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