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Article

A smaller olfactory bulb in a mouse model of Down syndrome.

Acta neurobiologiae experimentalis - 1 Jan 2020

Bontempi Pietro, Cisterna Barbara, Malatesta Manuela, Nicolato Elena, Mucignat-Caretta Carla, Zancanaro Carlo

Abstract excerpt

Persons with trisomy 21 (Down syndrome) present different phenotypes, including early neurodegeneration, which is prominent in the brain olfactory areas, and olfactory deficit. The use of in vivo techniques in animal models allows to characterize and follow up these slowly developing phenomena. We explored by means of magnetic resonance imaging the olfactory bulb of the Ts65Dn mouse, an established model of Down...

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PMID: 33350990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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