Article

Investigating Brain Alterations in the Dp1Tyb Mouse Model of Down Syndrome

2023-07-28

Abstract excerpt

<h4>ABSTRACT</h4> Down syndrome (DS) is one of the most common birth defects and the most prevalent genetic form of intellectual disability. DS arises from trisomy of chromosome 21, but its molecular and pathological consequences are not fully understood. In this study, we compared Dp1Tyb mice, a DS model, against their wild-type (WT) littermates of both sexes to investigate the impact of DS-related genetic abnor...

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Literature Corpus work: ae2d7723-97c8-5afe-b102-aa3bf3f2ef89
DOI: 10.1101/2023.07.26.550698

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