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Article

Molecular and Cellular Alterations in Down Syndrome: Toward the Identification of Targets for Therapeutics

1 Jan 2012

Abstract excerpt

Down syndrome is a complex disease that has challenged molecular and cellular research for more than 50 years. Understanding the molecular bases of morphological, cellular, and functional alterations resulting from the presence of an additional complete chromosome 21 would aid in targeting specific genes and pathways for rescuing some phenotypes. Recently, progress has been made by characterization of brain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22848846
DOI: 10.1155/2012/171639

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