Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Relevance of animal models in the study of human pathologies: a mouse model of Down syndrome].

Biologie aujourd'hui - 1 Jan 2010

Morice Elise

Abstract excerpt

Animal models provide a simplified representation of biological systems impossible to study directly in the human being. Regarding genetic pathologies, mouse models are the most studied since they enable to reproduce in animals the mutation of the gene or genes responsible for the disease and to study the phenotypic consequences. Down syndrome is a genetic disorder arising from the presence of a third copy of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 21
Share to Cognition Disorders
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down Syndrome

Share to Neuronal Plasticity

Share to Phenotype

Share to Reproducibility of Results

Source

Identifiers

PMID: 20950569
DOI: 10.1051/jbio/2010003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Relevance of animal models in the study of human pathologies: a mouse model of Down syndrome].PMID 20950569Read ↗

Rodent models in Down syndrome research: impact and future opportunities.Semantic proximity Read ↗

Down syndrome mouse models are looking up.Semantic proximity Read ↗

Molecular and Cellular Alterations in Down Syndrome: Toward the Identification of Targets for TherapeuticsSemantic proximity Read ↗

Vertebrate and Invertebrate Animal Models for the Study of Down SyndromeSemantic proximity Read ↗

Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndromeSemantic proximity Read ↗

Mouse Models for Down Syndrome-Associated Developmental Cognitive DisabilitiesSemantic proximity Read ↗

A new Down syndrome rat model races forward.Semantic proximity Read ↗

Is it possible to improve neurodevelopmental abnormalities in Down syndrome?Semantic proximity Read ↗

Mouse-based genetic modeling and analysis of Down syndromeSemantic proximity Read ↗

The power of comparative and developmental studies for mouse models of Down syndrome.Semantic proximity Read ↗

Models for Down syndrome: chromosome 21-specific genes in mice.Semantic proximity Read ↗

A mouse model for Down syndrome exhibits learning and behaviour deficitsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.